- Description
- Specifications
Catalog #: PKA-249
Description:
Soluble TIE-2 Mouse Recombinant fused with the Fc part of human IgG1 produced in CHO is a glycosylated disulfide-linked homodimer, polypeptide containing amino acids 119-740 amino acids and having a total molecular mass of 280 kDa. Mouse TIE-2/Fc monomer has a calculated molecular mass of approximately 105 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 140 kDa protein in SDS-PAGE under reducing conditions.
The TIE2 Fc Chimera is purified by proprietary chromatographic techniques.
Synonyms:
Angiopoietin-1 receptor precursor, Tyrosine-protein kinase receptor TIE-2, hTIE2, Tyrosine-protein kinase receptor TEK, p140 TEK, Tunica interna endothelial cell kinase, CD202b, VMCM, VMCM1, TIE2.
Source:
CHO Cells.
Purity:
Greater than 90.0% as determined by SDS-PAGE.
Solubility:
It is recommended to reconstitute the lyophilized TIE-2 Fc Chimera in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Formulation:
TIE-2 Fc Chimera was lyophilized from a concentrated (1 mg/ml) sterile solution containing 1x PBS.
Stability:
Lyophilized sTIE-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 °C. Upon reconstitution TIE-2 should be stored at 4 °C between 2-7 days and for future use below
-18 °C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Usage:
Denovo Biotechnology's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
