- Description
- Specifications
Catalog #: HSP-022
Synonyms:
HSPB8, H11, HMN2, CMT2L, DHMN2, E2IG1, HMN2A, HSP22, Heat shock protein beta-8, Alpha-crystallin C chain, Small stress protein-like protein HSP22, E2-induced gene 1 protein, Protein kinase H11, CRYAC.
Source:
Escherichia Coli.
Purity:
Greater than 95.0% as determined by SDS-PAGE.
Solubility:
It is recommended to reconstitute the lyophilized HSPB8 in sterile 18M?-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Formulation:
The HSPB8 protein was lyophilized from a concentrated (1mg/ml) solution containing 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 15mM ?-ME.
Stability:
Lyophilized HSPB8 although stable at room temperature for 3 weeks, should be stored desiccated below -18 °C. Upon reconstitution HSPB8 should be stored at 4 °C between 2-7 days and for future use below -18 °C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Activity:
Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSPB8.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Usage:
Denovo Biotechnology's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
References:
Title: Roles of ERK and NF-?B in Interleukin-8 Expression in Response to Heat Shock Protein 22 in Vascular Smooth Muscle Cells.
Publication: Korean J Physiol Pharmacol. 2008 Aug;12(4):171-176.
Link: http://synapse.koreamed.org/DOIx.php?id=10.4196/kjpp.2008.12.4.171&vmode=FULL
Applications: HSP22 induces IL-8 in VSMCs via ERK1/2.
