- Description
- Specifications
Catalog #: HOR-268
Description:
Lutenizing Hormone Releasing Hormone Human Recombinant is a heterodimeric, glycosylated, polypeptide chain consisting of two non-covalently linked subunits a and b of 92 and 121 amino acids respectively.
The carobhydrate chain attachment to the LHRH protein core accurs via N- but not O-linkage. The N-glycosilation sites are Asn-52 and Asn-78 for the a subunit and Asn-30 for the b subunit. The b chain has an N-glycosilation site and its structure and glycosilation pattern are very similar to that of pituitary LHRH.
The LHRH is purified by proprietary chromatographic techniques.
Synonyms:
Progonadoliberin-1, Progonadoliberin I, LHRH, GRH, GNRH, LNRH.
Source:
Saccharomyces cerevisiae.
Purity:
Greater than 99.0% as determined by RP-HPLC.
Formulation:
Each 165IU LHRH was lyophilized from with 98 mg sucrose, 1.66 mg phosphate dibasic, 0.1 mg phosphate monobasic, 0.1 mg tween 20 and 0.2 mg L-methionine.
Stability:
Lyophilized LHRH although stable at room temperature for 3 weeks, should be stored desiccated below -18 °C. Upon reconstitution LNRH should be stored at 4 °C between 2-7 days and for future use below
-18 °C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Activity:
The biological activity is determind by using the Van Hell Bioasssay described in the British Pharmacopeia.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Usage:
Denovo Biotechnology's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
